AFP (alpha-fetoprotein) tests are used to evaluate testicular cancer. The measurement of AFP in serum, along with serum hCG, is routine for monitoring patients with testicular cancer. Monitoring the rate of AFP clearance from serum after treatment is an indicator of the effectiveness of therapy. Conversely, the growth rate of progressive cancer can be monitored by serially measuring serum AFP concentration over time. Fasting is not required for this test. Take all medications as prescribed.