Estradiol is the predominant sex hormone present in females and is also found at lower levels in men. It represents the major estrogen in humans. Estradiol not only impacts reproductive and sexual functioning, but also affects other systems including bone health, heart health, nerves and metabolism. For women, it is important to compare the relationship between estradiol and progesterone in evaluating menopausal symptoms such as hot flashes, mood disorders, and aging skin. In men, high levels of estradiol are associated with abdominal fat, enlargement of the prostate and cardiovascular risk. In both men and women, low levels of estradiol are associated with osteoporosis. Fasting is not required for this test. Take all medications as prescribed.
Special Note: If you are supplementing with estradiol, it is important to take it approximately 2 hours prior to having blood drawn. Any type of contraceptives that contain hormones will invalidate hormone results.