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Propeptide of Brain Natriuretic Peptide (NT-proBNP)

Propeptide of Brain Natriuretic Peptide (NT-proBNP)

B-type natriuretic peptide (BNP) is a small protein secreted by the ventricles of the heart in response to excessive stretching of the heart muscles cells (myocytes). BNP is secreted into the blood when  heart is working hard. The N-terminal fragment of BNP is a highly sensitive marker for cardiac dysfunction.

An elevated NT-proBNP level always indicates the presence of an underlying cardiac disorder. It can even identify people with structural heart disease and cardiac dysfunction before symptoms begin. Even relatively low levels of NT-proBNP may be considered an index of increased cardiovascular risk since NT-proBNP abnormalities correlate well with development of progressive atherosclerosis. Fasting is not required for this test. Take all medications as prescribed.